Naltrexone and acamprosate combination in alcohol treatment
Posted on July 23, 2013
The use of Naltrexone and/or acamprosate can be helpful during alcohol treatment, however, to achieve the greatest success, individuals would benefit from incorporating psychological intervention. Evidence-based addiction treatment incorporates cognitive behavior therapy (CBT) which enables individuals to learn ways to cope with cravings and eventually have greater success for alcohol recovery.
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Naltrexone is an opioid antagonist that blocks the reward effects of alcohol consumption. The mechanism of acamprosate is less well-defined, but it may reduce unpleasant feelings (such as anxiety and tension) during withdrawal by blocking NMDA receptors. Previous research shows that acamprosate increases the number of individuals wh...
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