By Kenneth Anderson, MA Normal and Retrograde Neurotransmission Delta-9 THC (delta-9-tetrahydrocannabinol) and CBD (cannabidiol) are the two most commonly found cannabinoids in the cannabis plant. The plant contains over 100 other cannabinoids as well. THC and CBD both affect the endocannabinoid system. "Endo-" is a Greek prefix meaning "inside." "Endocannabinoid system" refers to all the systems of the body which contain cannabinoid receptors and are affected by cannabinoids. We will be primarily focused on the effects of cannabinoids in the central nervous system, and on the CB1 receptor, which is the main cannabinoid receptor there. Drugs like THC can affect the central nervous system because there are also naturally occurring cannabinoids in the central nervous system, the endo...

By Tom Horvath, PhD How can we explain the widespread expressed concern about US overdose deaths, coupled with our rather ineffective response to them? US overdose deaths may be the highest in the world. I will limit the following discussion to opiates, but alcohol, meth and multiple substance use are also of concern. I suggest that harsh and inaccurate beliefs about substance use and substance users have led many of the parts of our “system” for addressing substance problems into actions that increase overdose deaths rather than reduce them. In the remainder of this blog, I provide some details to support that idea. Buprenorphine and methadone: The medications most helpful for opiates are buprenorphine and methadone.  As it stands much less than half of the US individuals who cou...

By A. Tom Horvath, PhD Is this question sacrilegious? It should not be. AA has done much good in the world, and I expect it will continue to do so, for those who freely choose to attend it. In this article I point out what harm AA can do and might continue to do. Any activity has a cost benefit analysis, and it is generally reasonable to consider that analysis. The question this article asks has been discussed many times before. You can conduct an internet search for this title and get numerous hits. You might even find this one: https://www.practicalrecovery.com/prblog/aa-harmful/ (posted 10 years ago on 3/25/14). For AA not to be harmful it might need to have more control over its discussions and what its members say (as SMART Recovery aims to do). AA members should NO...

By Tom Horvath, PhD Stanton Peele suggested this idea in one of his recent blogs. As we await Super Bowl Sunday (2/11/24) the question seems worth re-visiting. It would require a careful analysis of outcomes from pro football and substance use to provide an accurate comparison. The data about substance problems is easy to find. Pro football’s data is harder to find, but generally we know that playing football can result in concussions, broken bones, chronic traumatic encephalopathy (CTE), and other injuries. For further details search for the NFL concussion settlement. However, it seems unlikely than an accurate comparison between pro football and substance use will occur because professional football is popular, and substance use seems to be unpopular. We often condemn substance ...

By Tom Horvath, PhD Boredom is the perception of being under-stimulated. We all have optimal levels of stimulation (some generally want more, some generally less). Whatever your level, when you are not getting enough, you are bored (and when over-stimulated, you may be stressed). Boredom is often considered an undesirable state. However, let’s start with its advantages. If not much is going on in your immediate world, you have time to consider the larger context of your life. It is easy to lose track of what is more important than day-to-day and moment-to-moment issues. If bored you have a moment to consider what is important, rather than just immediate or urgent. When feeling bored you might say, “I’m glad nothing is pressing on me at the moment; I can think about the bigger p...

By Tom Horvath, PhD A recent scientific paper analyzed the responses from nearly 10K individuals who identify themselves as “in recovery” from substance problems. In recent years the addiction recovery field has been considering how to define “recovery.” Five major organizations have offered definitions or attempts at definitions. However, there is not much data on this issue. Two previous studies have looked at how individuals in recovery define it. The present study is an advance because it identified 30 sub-groups, based on socio-demographics, substance use problems, and help-seeking history. Each sub-group was analyzed for which components of a recovery definition might be common for that sub-group. The second study had averaged all subjects together, thus losing some of the diff...

By Kenneth Anderson All too often I hear people erroneously lay the blame for the current war on drugs on Nixon; however, this is historically inaccurate. The focus of Nixon's war on drugs was treatment, and under Nixon, the harsh drug laws of the 1950s were eased. Ronald Reagan was the true architect of the evil known as today's war on drugs. Let's start by looking at some historical background. The US Rise of Substance Use There was an explosive growth in the use of marijuana from 1967 to 1979, with LSD bringing up the rear. Although marijuana and LSD were promoted in the early 1960s by both Timothy Leary at Harvard and Ken Kesey at his ranch in rural La Honda, California, about 42 miles from San Francisco, their influence was quite local and had little impact on the US as a whol...

By Tom Horvath, PhD This blog will focus less on physical skills (like playing the piano or hitting a baseball) and more on “psychological skills” like being assertive. Physical and psychological skills are not entirely distinct. Your body will need to play its part in a psychological skill. For instance, you would need to say “no thanks, I’m not interested in that” with your mouth. The physical skills needed to accomplish a psychological skill are typically already well known to you. You just need to use them! Without further ado, let's take a look at practicing psychological skills. Practicing Psychological Skills #1: Interpersonal Skills Nevertheless, the physical aspect of a psychological skill can be a good place to start. To stay with our example, you could practice sayin...

By Tom Horvath “Analysis paralysis” is another term for “overthinking” a decision. We face many decisions in life. Some we make too quickly (like acting on addictive impulses), and some too slowly. This blog focuses on making decisions too slowly. (We also leave out the sequence of smaller decisions we might make over years, that lead to an occupation, a partner, or a hometown we may or may not be satisfied with) How can we match the amount of time and energy we devote to a decision with the importance of the decision? Let’s focus on decisions like what movie to see, what birthday card or present to purchase, what meal to order, what color to paint a room, or how to state something (such as when writing an email or blog!). If you start “going down a rabbit hole” in your decision-m...

A Closer Look at the Rat Park Experiment, Part 2 By Kenneth Anderson, MA Part 1 reviewed some of the historical background which led up to the rat park studies. Part 2 reviews the rat park studies themselves. Part 3 will take a look at where we have gone since. Bruce K. Alexander's first rat park study was published in 1978. The subjects were 32 albino Wistar rats (18 males and 14 females). After weaning, 10 of the rats (six males and four females) were placed in solitary confinement in standard laboratory cages. Twenty-two of the rats (12 males and 10 females) were placed in rat park. Rat park was an open-topped plywood box with 95 square feet of floor space covered in sawdust where rats could play, fight, and have sex with each other just like they did in their natural enviro...