Modafinil with CBT May Improve Drug Rehab for Gay Men with HIV

Methamphetamine use has been linked to increased risk of human immunodeficiency virus (HIV) among gay men. Methamphetamine is a highly addictive stimulant that may lower inhibitions, increase sexual arousal, and lead to risky sexual behavior such as unprotected sex. Further, methamphetamine may be injected, and needle-sharing is also a risk factor for HIV. These two […]
Drug Rehab May Soon Include Pharmacogenetics

Pharmacogenetics looks at genetic variation to predict individual differences in response to medications. Individuals may metabolize the same medication in different ways, and their genotype may indicate some of these differences in drug metabolism. Proponents of pharmacogenetics hope that this relatively new field of study will lead to increased efficacy and safety for a wide […]
Will an Anti-cocaine Vaccine Improve Drug Treatment?

A clinical trial supported by the National Institute on Drug Abuse (NIDA) marks the first successful, placebo-controlled demonstration of a vaccine against illicit drug addiction. The anti-cocaine vaccine causes the immune system to produces antibodies that attach to cocaine molecules, preventing them from entering the brain. Thus, the vaccine blocks the drug’s effect. The […]
Aripiprazole (Abilify) in Alcohol Treatment & Recovery

Aripiprazole (Abilify) has been approved by the FDA for the treatment of schizophrenia and acute manic and mixed episodes of bipolar disorder and as an adjunct for the treatment of major depressive disorder. Although other FDA-approved atypical antipsychotics (clozapine, risperidone, olanzapine, quetiapine, and ziprasidone) antagonize the D2 dopamine receptor, aripiprazole acts as a dopamine receptor […]
Predictors of response to naltrexone in alcohol rehab

Naltrexone is commonly prescribed in alcohol rehab. It is an opioid receptor antagonist that blocks opioid receptors and thus blocks the feeling of pleasure derived from alcohol consumption. Several double-blind clinical trials have shown that naltrexone is more effective than placebo in treatment for alcohol dependence. However, naltrexone may not work well for everyone. Its […]
High-dose baclofen for alcohol treatment

Oliver Ameisen, an associate professor of medicine and cardiologist at Weill Medical College of Cornell University, reported in Alcohol and Alcoholism that he successfully used high-dose baclofen for alcohol treatment and achieved complete and prolonged suppression of symptoms of his own alcohol dependence (2005). You may also be interested in: Ameisen had been diagnosed with […]