Predictors of response to naltrexone in alcohol rehab
Posted on July 23, 2013
Naltrexone is commonly prescribed in alcohol rehab. It is an opioid receptor antagonist that blocks opioid receptors and thus blocks the feeling of pleasure derived from alcohol consumption. Several double-blind clinical trials have shown that naltrexone is more effective than placebo in treatment for alcohol dependence. However, naltrexone may not work well for everyone. Its effectiveness varies among individuals. This has led some researchers to speculate that perhaps not all alcohol dependent individuals derive pleasure from an increase in endogenous opioids after alcohol consumption; perhaps there is a subtype of alcohol dependent individuals which may derive more benefit from naltrexone treatment. Certain clinical predictors might be able to identify individuals who would derive th...
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