Cigarette smoking is common among individuals with alcohol use disorder (AUD), and research suggests that smoking may interfere with alcohol recovery. Mon et. al. found that smoking slows the healing of brain damage during alcohol recovery (2009). Several studies have shown that AUD can damage the brain. AUD brain damage, commonly visible in the frontal cortex and parietal cortex, is at least partially reversible with sustained abstinence from drinking. What Can an MRI Reveal About Smoking and Alcohol Recovery? Magnetic resonance imaging (MRI) can show the extent of brain-damaging by illustrating blood flow. Cerebral perfusion is a measure of the blood flow to brain tissue. Blood not only carries nutrients to the brain but also carries away metabolic byproducts. Good blood flow ind...

Aripiprazole (Abilify) has been approved by the FDA for the treatment of schizophrenia and acute manic and mixed episodes of bipolar disorder and as an adjunct for the treatment of major depressive disorder. Although other FDA-approved atypical antipsychotics (clozapine, risperidone, olanzapine, quetiapine, and ziprasidone) antagonize the D2 dopamine receptor, aripiprazole acts as a dopamine receptor partial agonist. Might a dopamine receptor partial agonist have a useful role in alcohol recovery? Antagonist vs. Agonist An agonist binds to a specific receptor and triggers a response that often mimics the response of another drug or naturally occurring substance. For example, methadone is an opioid agonist that mimics the effects of opiates. Antagonists, on the other hand, bind to the ...

Among men who seek alcohol recovery, there are high rates of co-occurring alcohol dependence and intimate partner violence (IPV). IPV may include physical abuse, sexual abuse, threats, and emotional abuse directed toward current and former spouses and dating partners. A sensible approach for alcohol treatment for these men would need to include interventions that address both drinking and violence. Older Studies Show Drinking Increases Physical Abuse Previous studies show that drinking increases physical abuse. In 2003, for example, Fals-Stewart (2003) conducted a study of 137 men which found that men who drink alcohol and have a predisposition for IPV are more likely to be violent on days when they drink alcohol. The study found that the odds of any male-to-female aggression were eig...

Because alcohol use disorders are common among driving-while-intoxicated (DWI) offenders, a DWI arrest may serve as an opportunity for psychological screening and subsequent alcohol treatment. Holt et. al. examined the Beck Depression Inventory (BDI) as a tool for predicting intervention outcomes in first-time DWI offenders. The BDI is a multiple-choice self survey consisting of 21 questions. It is the most widely used questionnaire for measuring the severity of depression. Survey questions are related to affective depressive symptoms such as pessimism, guilt, self-dislike, suicidal thoughts, and feelings of worthlessness, as well as physical symptoms such as anhedonia (loss of pleasure), crying, agitation, loss of energy, change in sleep patterns, change in appetite, difficulty conc...

Do you feel anxious when you’re in the spotlight or under scrutiny? According to a recent study from researchers at Yale University and Florida State University, social anxiety – and fear of scrutiny, specifically – appears to serve as a risk factor for alcohol use disorders (Buckner & Schmidt, 2009). Future research into how observation anxiety can lead to excessive alcohol use will likely provide useful guidance for alcohol recovery. For now, it appears that individuals with both observation anxiety and excessive alcohol use will likely need to learn to manage their observation anxiety in order to achieve a stable alcohol recovery. Social anxiety disorder (SAD) and alcohol use disorders (AUD) are highly comorbid. According to one study, 48 percent of individuals with a lifet...

Binge Drinking, Daily Drinking and Liver Disease   If you are aiming to establish an alcohol recovery by moderating alcohol as opposed to abstaining from alcohol, you may be tempted to believe that as long as you do not binge drink you will not experience any major negative health consequences.  Although binge drinking is clearly risky, the study reported on in this article found that daily drinking that was heavy (but not at binge levels) also can lead to liver disease.  There are other risks to consider also.  Although some studies suggest that moderate consumption of alcohol may offer cardiovascular benefits, other studies have found that regular drinking increases the risk of diseases such as cancer and liver disease. Is binge drinking causing problems in your life? We c...

What are the effects of cannabis on alcohol recovery? Many alcohol dependent individuals relapse after a period of abstinence in alcohol recovery. Researchers have used the reinstatement paradigm as an animal model of relapse. Animals are exposed to certain stimuli to test whether they reinstate previously extinguished responses, such as alcohol-seeking behavior. Lab rats, for example, will drink beer to the point of having withdrawal symptoms upon termination. Recent studies have found that synthetic cannabinoids (but not delta-9-THC, the main psychoactive constituent in marijuana) can reinstate previously extinguished drug-seeking behavior in lab rats (for cocaine, heroin, and methamphetamine). Since cannabis is often used with alcohol in social settings, a team of researchers in Aust...

What is the relationship between alcohol and sense of smell? Olfactory impairment is one of the many potential side effects of alcohol dependency. In a non 12 step approach to recovery, individuals have the opportunity to completely abstain from alcohol and possibly decrease any potential olfactory impairments. Olfaction — the sense of smell — not only allows individuals to stop and smell the roses but also saves lives. Olfaction, for instance, might alert one to an unsafe food product or smoke from a fire. Unfortunately, an individual in alcohol recovery might not be awakened by the odor of smoke. Several previous studies have suggested that chronic alcohol use may damage olfactory function, but little is known about how this occurs. Previous studies indicate that alcohol-dependent ...

Naltrexone is commonly prescribed in alcohol rehab. It is an opioid receptor antagonist that blocks opioid receptors and thus blocks the feeling of pleasure derived from alcohol consumption. Several double-blind clinical trials have shown that naltrexone is more effective than placebo in treatment for alcohol dependence. However, naltrexone may not work well for everyone. Its effectiveness varies among individuals. This has led some researchers to speculate that perhaps not all alcohol dependent individuals derive pleasure from an increase in endogenous opioids after alcohol consumption; perhaps there is a subtype of alcohol dependent individuals which may derive more benefit from naltrexone treatment. Certain clinical predictors might be able to identify individuals who would derive th...

Nausea, abdominal discomfort, and other gastrointestinal symptoms are commonly reported by individuals after drinking alcoholic beverages. The alcohol itself may cause gastrointestinal problems by affecting the gastric emptying process. Researchers at the University Hospital of Heidelberg at Mannheim in Germany conduced a systematic study of the effects of ethanol, alcoholic beverages, and the non-alcohol components of alcoholic beverages on the gastric emptying of solid meals in the human body, and the results suggest that alcohol rehab may improve gastrointestinal problems (Franke et. al., 2005). The researchers recruited 16 fasting, healthy, male participants who received once weekly 300 ml of pure ethanol, beer, red wine, glucose, and water in a random order. The solutions were g...