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Pharmacogenetics looks at genetic variation to predict individual differences in response to medications. Individuals may metabolize the same medication in different ways, and their genotype may indicate some of these differences in drug metabolism. Proponents of pharmacogenetics hope that this
Will an anti-cocaine vaccine improve drug treatment?
A clinical trial supported by the National Institute on Drug Abuse (NIDA) marks the first successful, placebo-controlled demonstration of a vaccine against illicit drug addiction. The anti-cocaine vaccine causes the immune system to produces antibodies which attach to cocaine molecules,
Predictors of response to naltrexone in alcohol rehab
Naltrexone is commonly prescribed in alcohol rehab. It is an opioid receptor antagonist that blocks opioid receptors and thus blocks the feeling of pleasure derived from alcohol consumption. Several double-blind clinical trials have shown that naltrexone is more effective than
High-dose baclofen for alcohol treatment
Oliver Ameisen, an associate professor of medicine and cardiologist at Weill Medical College of Cornell University, reported in Alcohol and Alcoholism that he successfully used high-dose baclofen as an alcohol treatment and achieved complete and prolonged suppression of symptoms of
Kudzu vine extract may prove useful in alcohol treatment
Daidzin, a compound found in the kudzu vine, interferes with the metabolization of alcohol and produces effects similar to those of the anti-drinking drug Antabuse. Dr. Ting-Kai Li of Duke University and Dr. Ivan Diamond of the University of California
Naltrexone and acamprosate combination in alcohol treatment
The use of Naltrexone and/or acamprosate can be helpful during alcohol treatment, however, to achieve the greatest success, individuals would benefit from incorporating psychological intervention. Evidence-based addiction treatment incorporates cognitive behavior therapy (CBT) which enables individuals to learn ways to
A one-year trial of naltrexone vs. disulfiram in alcohol treatment
Using evidence based addiction treatment, individuals can learn a self-empowering approach to overcome addiction. Naltrexone and disulfiram are both used as deterrent agents in Naltrexone is an opioid receptor agonist that reduces the euphoria associated with alcohol consumption and thus
